簡 介 |
利用表面電漿共振原理,即時追蹤生物分子之間的交互作用。此技術不需額外標記物,可以測得蛋白質、核酸、小分子藥物、糖類、脂質的結合與解離情況,具有以下優點,高靈敏:蛋白質結合常數(ka)可達
3x109 M-1S-1
多種應用:Kinetics/affinity
characterization, kinetics/affinity screening, single-cycle kinetics,
LMW interaction analysis, fragment screening, epitope mapping,
immunogenicity, concentration analysis, calibration-free concentration
analysis, thermodynamics, comparability, sample recovery MS |